Wednesday, April 10, 2013

AT&T announces 20 new LTE locations

AT&T LTE

AT&T dumps a bucket full of LTE location news, both currently active cities and coming soon announcements

AT&T just sent out 20 press releases with a bunch of LTE announcements. There's a lot to digest, so allow us to break it all down in one place for easy reading.

New LTE cities that are currently active:

New LTE cities coming this summer:

There's no word on when exactly during the summer these will light up, but I'm sure AT&T will remind us again when they go live -- or you fine folks will let us all know the minute it drops. 

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/NdlDuC22lZU/story01.htm

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Obama budget: Spending cuts, higher smokers' taxes

President Barack Obama, accompanied by acting Budget Director Jeffrey Zients, speaks in the Rose Garden of the White House in Washington, Wednesday April 10, 2013, to discuss his proposes fiscal 2014 federal budget. (AP Photo/Susan Walsh)

President Barack Obama, accompanied by acting Budget Director Jeffrey Zients, speaks in the Rose Garden of the White House in Washington, Wednesday April 10, 2013, to discuss his proposes fiscal 2014 federal budget. (AP Photo/Susan Walsh)

President Barack Obama, accompanied by acting Budget Director Jeffrey Zients, speaks in the Rose Garden of the White House in Washington, Wednesday April 10, 2013, to discuss his proposes fiscal 2014 federal budget. (AP Photo/J. David Ake)

Graphic shows major points of President Obama's FY 2014 budget and comparisons with other plans

House Speaker John Boehner of Ohio meets with reporters on Capitol Hill in Washington, Wednesday, April 10, 2013, following a Republican strategy session, and the release of President Barack Obama's proposed fiscal 2014 federal budget. (AP Photo/J. Scott Applewhite)

President Barack Obama and acting Budget Director Jeffrey Zients, leave the Rose Garden of the White House in Washington, Wednesday April 10, 2013, after he president discussed his proposes fiscal 2014 federal budget. (AP Photo/Charles Dharapak)

(AP) ? Mixing modest curbs on spending with tax increases reviled by Republicans, President Barack Obama proposed a $3.8 trillion budget on Wednesday that would raise taxes on smokers and wealthy Americans and trim Social Security benefits for millions.

Obama's 2014 blueprint combines a $242 billion infusion of new spending for road and rail projects, early education and jobs initiatives ? all favored by Democrats ? with longer-term savings from programs including Medicare and the military. It promises at least a start in cutting huge annual federal deficits.

The president pitched his plan as a good-faith offer to his GOP rivals since it incorporates a proposal he made to Republicans in December that wasn't radically different from a GOP plan drafted by House Speaker John Boehner. But it follows January's bitterly fought 10-year, $600 billion-plus tax increase that has stiffened GOP resolve against further tax hikes.

"I have already met Republicans more than halfway, so in the coming days and weeks I hope that Republicans will come forward and demonstrate that they're really as serious about the deficit and debt as they claim to be," Obama said.

He was having a dozen Senate Republicans to the White House for dinner Wednesday evening in hopes of building a dialogue on the budget and other topics.

After four years of trillion-dollar-plus deficits in his first term, Obama's plan projects a $973 billion deficit for the current budget year and red ink of $744 billion for the 2014 fiscal year starting in October. By 2016, the deficit is seen as dropping below 3 percent of the size of the economy, a level that many economists say is manageable.

Obama cast his budget as a compromise offer that would bridge differences between Republicans and their desire for reducing government spending and Democrats who want more revenue from taxpayers. But it's difficult to overstate the gulf between Obama and the conservatives who are in the GOP driver's seat in Congress.

While the budget proposal will not prompt any immediate congressional action, it will probably surface this summer when Republicans are expected to demand additional reductions in the deficit in exchange for increasing the nation's borrowing authority.

Obama claims $1.8 trillion in deficit savings over the coming decade, but the budget tables show the savings are actually $1.4 trillion. And $1.2 trillion of that is devoted to reversing automatic, across-the-board spending cuts required because of Washington's inability to follow up a 2011 budget pact with further deficit action.

"This is worse than a status quo budget," said House Budget Committee Chairman Paul Ryan, R-Wis. He said it has about $1 trillion in new taxes, $1 trillion in new spending with deficit reduction of only $119 billion over 10 years under GOP math that sorts through questionable interpretations employed by the White House.

For instance, Obama claims $167 billion in lower war costs ? money the administration never intended to spend ? and uses that "savings" for road projects and other undertakings it bills as jobs initiatives.

The real cuts include $400 billion scrubbed from health care programs like Medicare over the coming decade, including cuts in payments to drug companies and higher Medicare premiums for people who are better off.

The administration would modestly cut the annual operating budgets for both the Pentagon and domestic agencies while reprising ideas like higher Transportation Security Administration fees on airline tickets, the end of Saturday mail delivery and higher pension contributions for federal workers.

"He does deserve some credit for some incremental entitlement reforms," said Boehner, R-Ohio. "But I would hope that he would not hold hostage these modest reforms for his demand for bigger tax hikes. Listen, why don't we do what we can agree to do?"

That's not the way it works, countered Gene Sperling, the director of Obama's National Economic Council. "The offer that is there for Speaker Boehner is not an a la carte menu."

And Rep. Chris Van Hollen, D-Md., said he had reservations about the White House making concessions without getting anything in return. He said, "The president will have to remain firm in his insistence that this is a package deal."

The White House budget claims $580 billion in tax increases on the wealthy over 10 years, including a 28 percent cap on itemized deductions that's never gotten anywhere on Capitol Hill.

The total climbs closer to $1 trillion in tax increases after adding in ideas like a 94 cents-per-pack increase in taxes on cigarettes, changes for corporate foreign earnings, slower inflation adjustments to income tax brackets, elimination of oil and gas production subsidies, an increase in the estate tax, a new "financial crisis responsibility" fee on banks and new taxes on trading of exotic financial instruments known as derivatives.

Republicans predictably slammed Obama's plan for its tax increases, while his Democratic allies generally held their tongues over cuts to Social Security benefits.

"It's not the budget I would write on my own, and it includes several policies that I don't think are the best ways to tackle the deficit and debt," said Senate Budget Committee Chairman Patty Murray, D-Wash.

Reacting more strongly, the senior citizens advocacy group AARP said it was "deeply dismayed that President Obama would propose cutting the benefits of current and future Social Security recipients, including children, widows, veterans and people with disabilities, to reduce the deficit." And AFL-CIO President Richard Trumka, whose organization spent tens of millions of dollars helping re-elect Obama, called the cuts "wrong and indefensible."

The Social Security cuts would come from a slightly stingier inflation adjustment known as "chained CPI" that would reduce annual cost-of-living increases for a variety of programs by about 0.3 percentage points a year. It would reduce federal spending on government programs over 10 years by $130 billion and promises to save far more in subsequent decades.

Once the change was fully phased in, Social Security benefits for a typical middle-income 65-year-old would be about $136 less a year, according to an analysis of Social Security data. At age 75, annual benefits under the new index would be $560 less. But after age 75, Social Security recipients would receive larger-than-scheduled benefit increases by 0.5 percentage points a year through age 85.

Obama promises to ease the burden of the proposal on the poor and the very elderly by not applying it to programs meant for low-income Americans. That means annual increases in assistance programs such as Social Security Supplemental Security Income and Pell Grants for student aid would not be calculated by using the lower inflation formula.

Despite Obama's vows not to raise taxes on the middle class, the chained CPI proposal also would result in higher taxes because tax brackets would be adjusted for inflation more slowly, with much of the effect felt by middle class taxpayers. The provision would raise about $100 billion over 10 years. At the same time, raising the cigarette tax from $1.01 to 1.95 per pack would be disproportionally felt by the poor. That tax increase would raise $78 billion over 10 years.

Obama's plan generally tracks a nonbinding budget measure that passed the Senate last month, though Democrats controlling the chamber left out the chained CPI proposal.

House Republicans, by contrast, muscled through a far more austere plan in March that contains big cuts to Medicaid and would reduce domestic agency budgets by about 20 percent below levels contemplated in a hard-fought 2011 budget pact that set tight "caps" on spending passed by Congress each year.

"I don't think we should be talking about grand bargains because that implies the president and Senate Democrats are ready to embrace fundamental entitlement reform, which they have shown absolutely no indication of doing," said House Budget Chairman Ryan, his party's vice presidential nominee last year.

Such pessimism is also felt by Democrats. Asked this week about the prospects for a broad budget deal, Murray said: "I think we're a long ways from there right now."

___

Associated Press writers Martin Crutsinger, Donna Cassata and Julie Pace contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-04-10-Obama%20Budget/id-8122185311d54d95b3387bd31521821c

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Space programs need new approach, Air Force leader says

By Andrea Shalal-Esa

COLORADO SPRINGS, Colorado (Reuters) - The military needs a new approach to developing and buying the satellites that are critical to every military operation, a top Air Force general said on Tuesday, citing growing threats in space and increasing budget pressures closer to earth.

"This time that we're in today absolutely begs for change," General William Shelton, who heads Air Force Space Command, told hundreds of industry executives at the annual National Space Symposium in Colorado Springs, Colorado. "There are storm clouds that are on the horizon."

Shelton said the United States faced a fundamentally altered environment in space, including the threat of a growing amount of space junk and possible hostile acts by enemy nations, coupled with funding problems that could derail key programs.

Military space programs have stabilized after years of massive cost overruns and schedule delays triggered by technical challenges, but tighter budgets and evolving threats are putting a bigger emphasis on affordability for future programs.

Air Force officials are promoting an approach called disaggregation, which would shift the focus to smaller, less complex satellites, at least for some missions, given problems with larger, more complex satellites built in recent years.

They are also studying other options, including buying services from commercial providers and putting government sensors aboard other satellites. Such options are being considered for a new weather satellite.

Northrop Grumman Corp, Boeing Co, Lockheed Martin Corp, and smaller players such as Harris Corp, Moog Inc, ITT Exelis Corp and Orbital Sciences Corp are trying to position themselves to benefit from any change in the Air Force's acquisition approach.

"We see a very steep declining budget," Shelton told reporters after his speech at the conference. "It just speaks very loudly that we need to consider disaggregation."

Mandatory budget cuts that took effect on March 1 have already forced the Air Force to shut down two of six radar receivers that provide data about satellites and debris in space, and cut 100 contractors who worked at the command's headquarters, halving the staff there, officials said.

Shelton told reporters that Air Force Space Command had to cut its fiscal 2013 budget by $508 million under sequestration, and further cuts were likely in coming years.

He declined to give details of the fiscal 2014 budget to be released on Wednesday, but said funding reductions in fiscal year 2015 and beyond would entail some "very tough choices."

For example, Shelton suggested that a new ground-based radar space fence program for which Lockheed Martin Corp and Raytheon Co have been competing might not be funded. The system tracks satellites and space debris.

Shelton said a contract award had been expected in the next month or two, but the program could be vulnerable to cuts in fiscal 2015 and beyond because it was not yet under contract.

He said he favored continuing work on the new space fence, but there were competing priorities within the Air Force budget - including the F-35 fighter built by Lockheed, a new Boeing refueling tanker and development of a new long-range bomber.

"Some serious decisions need to be made in terms of priority," he said. "If you decided you weren't going to continue and award that contract, those investment dollars could be available for investment in other things."

Michael Hamel, a former senior Air Force official and senior vice president at Orbital Sciences, welcomed the Air Force's increasing openness to alternate approaches, but said industry needed tangible evidence sooner than fiscal 2015.

"For a company like ours, two years can be an eternity," Hamel told Reuters at the conference, urging the Air Force to award initial contracts that showed its intent. "There has to be a sense of urgency. Let's take a few steps down this path."

But Rick Ambrose, who heads Lockheed's space division, urged caution, noting that past shifts in Air Force space acquisition had resulted in problems because they curtailed funding for existing programs. Lockheed builds the Air Force's missile warning, secure communications and global positioning satellites, but is also exploring alternative options.

"We're not against disaggregation. We want to make sure we don't quickly rush to a paper-based idea. We want to think it through," Ambrose told Reuters.

(Reporting by Andrea Shalal-Esa; Editing by Lisa Shumaker)

Source: http://news.yahoo.com/space-programs-approach-air-force-leader-says-010854849--sector.html

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Lawmaker invites gun makers to relocate to RI

PROVIDENCE, R.I. (AP) -- A Republican state lawmaker is inviting firearms manufacturers to relocate to Rhode Island from other states he says are "hostile" to gun owners' rights.

House Minority Leader Brian Newberry of North Smithfield made the invitations Monday to Hartford, Conn.-based Colt's Manufacturing Co. and Beretta USA Corp. in Accokeek, Md.

Conservative Republicans across the country also are trying to lure gun makers in case they want to move out of states like Connecticut and Maryland that have passed strict new gun laws.

Newberry says Rhode Island has vacant factories that could support gun manufacturing, and the state would benefit from the jobs.

His invitation came on the eve of Tuesday's planned announcement of nine gun control bills by Rhode Island officials. Newberry says the bills would do nothing to deter criminals.

Source: http://news.yahoo.com/lawmaker-invites-gun-makers-relocate-155343672.html

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Tuesday, April 9, 2013

AACR news: Six2 homeoprotein allows breast cancer cells to detach and metastasize

AACR news: Six2 homeoprotein allows breast cancer cells to detach and metastasize [ Back to EurekAlert! ] Public release date: 9-Apr-2013
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Contact: Garth Sundem
garth.sundem@ucdenver.edu
805-559-2023
University of Colorado Denver

'Here we show for the first time that Six2 causes breast cancer progression,' says researcher

In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate and survive their transition through the bloodstream to faraway sites of metastasis.

"Here we show for the first time that Six2 causes breast cancer progression. It's this metastasis, especially to the lung, that can eventually be deadly and so perhaps even more so than affecting the size of the primary tumor, we are especially excited to present this new information about metastasis," says first author Chu-An Wang, PhD, postdoc in the lab of CU Cancer Center investigator Heide Ford, PhD, the paper's senior author.

The Six2 gene codes for a transcription factor that regulates cell growth needed in developing kidney tissues, but then silenced in the healthy, adult body. Some breast cancer cells have discovered a way to reactivate this Six2 gene, which allows them to survive detachment from their tissue of origin and the programmed cell death known as anoikis that makes most wandering cells self-destruct.

Wang and colleagues knocked down Six2 expression in breast cancer cells and showed that the cells' ability to metastasize in mouse models was much reduced. Interestingly, Six2 knockdown did nothing for the cells' ability to grow at the site of origin. Corroborating the claim of Six2's role in metastasis is its correlation with poor prognosis in human breast cancer tissues of 1881 samples examined from the GOBO database, the breast cancer tissues higher in Six2 were simply more aggressively metastatic.

"We're now working to discover Six2's target genes," Wang says. "For example, we hypothesize an effect on the expression of E-Cadherin, whose loss has been implicated in the metastatic potential of many cancers."

###


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


AACR news: Six2 homeoprotein allows breast cancer cells to detach and metastasize [ Back to EurekAlert! ] Public release date: 9-Apr-2013
[ | E-mail | Share Share ]

Contact: Garth Sundem
garth.sundem@ucdenver.edu
805-559-2023
University of Colorado Denver

'Here we show for the first time that Six2 causes breast cancer progression,' says researcher

In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate and survive their transition through the bloodstream to faraway sites of metastasis.

"Here we show for the first time that Six2 causes breast cancer progression. It's this metastasis, especially to the lung, that can eventually be deadly and so perhaps even more so than affecting the size of the primary tumor, we are especially excited to present this new information about metastasis," says first author Chu-An Wang, PhD, postdoc in the lab of CU Cancer Center investigator Heide Ford, PhD, the paper's senior author.

The Six2 gene codes for a transcription factor that regulates cell growth needed in developing kidney tissues, but then silenced in the healthy, adult body. Some breast cancer cells have discovered a way to reactivate this Six2 gene, which allows them to survive detachment from their tissue of origin and the programmed cell death known as anoikis that makes most wandering cells self-destruct.

Wang and colleagues knocked down Six2 expression in breast cancer cells and showed that the cells' ability to metastasize in mouse models was much reduced. Interestingly, Six2 knockdown did nothing for the cells' ability to grow at the site of origin. Corroborating the claim of Six2's role in metastasis is its correlation with poor prognosis in human breast cancer tissues of 1881 samples examined from the GOBO database, the breast cancer tissues higher in Six2 were simply more aggressively metastatic.

"We're now working to discover Six2's target genes," Wang says. "For example, we hypothesize an effect on the expression of E-Cadherin, whose loss has been implicated in the metastatic potential of many cancers."

###


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-04/uocd-ans040613.php

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Smoking may negatively impact kidney function among adolescents

Apr. 8, 2013 ? Exposure to tobacco smoke could negatively impact adolescent kidney function; this is according to a new study led by a team of researchers at the Johns Hopkins Bloomberg School of Public Health and the Johns Hopkins Children's Center. They examined the association between exposure to active smoking and kidney function among U.S. adolescents and found the effects of tobacco smoke on kidney function begin in childhood. The results are featured in the April 2013 issue of Pediatrics.

"Tobacco use and exposure to secondhand tobacco smoke are major health problems for adolescents, resulting in short-term and long-term adverse health effects," said Ana Navas-Acien, MD, PhD, senior author of the study and an associate professor with the Bloomberg School's Department of Environmental Health Sciences. "In this nationally representative sample of U.S. adolescents, exposure to tobacco, including secondhand smoke and active smoking, was associated with lower estimated glomerular filtration rates -- a common measure of how well the kidneys are working. In addition, we found a modest but positive association between serum cotinine concentrations, a biomarker of tobacco exposure, among first-morning albumin to creatinine ratio. These findings further support the conclusion that tobacco smoke may damage the kidneys."

Using a cross-sectional study of 7,516 adolescents ages 12 to 17, the authors assessed participant tobacco use and exposure to secondhand smoke through self-reported data from a home questionnaire and serum cotinine. Participants who reported having smoked "at least one day" in the last month or "at least one cigarette" in the last month, or those who had serum cotinine concentrations over 10 ng/ml were classified as active smokers. Secondhand smoke exposure was defined as non-active smokers who reported living with at least one person who smoked, or who had cotinine levels greater than or equal to 0.05 ng/ml, but less than or equal to 10 ng/ml even if they reported not living with a smoker. Participants with serum cotinine levels below 0.05 ng/ml, not living with a smoker and not smoking in the last month, were classified as unexposed to tobacco.

Earlier studies examining U.S. adolescent tobacco exposure have indicated more than 600,000 middle school students and 3 million high school students smoke cigarettes and 15 percent of non-smoking adolescents report exposure to secondhand smoke at home. Among adolescents, active smoking has been associated with increased asthma risk, reduced lung function and growth, early atherosclerotic lesions and increased cancer risk as well as premature mortality in adulthood. According to Centers for Disease Control and Prevention, smoking is also a risk factor for several autoimmune diseases, including Crohn's disease and rheumatoid arthritis.

"Small changes in the distribution of estimated glomerular filtration rate levels in the population could have a substantial impact in kidney-related illness, as it is well known for changes in blood pressure levels and hypertension-related disease. Evaluating potential secondhand smoke exposure and providing recommendations to minimize exposure should continue to be incorporated as part of children's routine medical care," noted Jeffrey Fadrowski, MD, MHS, co-author of the study and an assistant professor in Pediatric Nephrology at the Johns Hopkins School of Medicine.

"Tobacco as a chronic kidney disease risk factor is of great concern given the high prevalence of use and the chronicity that most often accompanies this exposure. Protecting young people from active smoking is essential since nearly 80 percent of adults who smoke begin smoking by 18 years of age," said Navas-Acien.

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The above story is reprinted from materials provided by Johns Hopkins University Bloomberg School of Public Health, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Esther Garc?a-Esquinas, Lauren F. Loeffler, Virginia M. Weaver, Jeffrey J. Fadrowski, and Ana Navas-Acien. Kidney Function and Tobacco Smoke Exposure in US Adolescents. Pediatrics, 2013 DOI: 10.1542/peds.2012-3201d

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/nW0pbiakyh8/130408152955.htm

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Monday, April 8, 2013

Transform an LED Flashlight into an Affordable Ice Light for Beautiful, Evenly Lit Photos

Transform an LED Flashlight into an Affordable Ice Light for Beautiful, Evenly Lit PhotosPart of taking great photos is great lighting, which can be tough to come by if you don't have a lot of money to spend. Thankfully, this light wand produces soft, even lighting thanks to an LED flashlight in the hilt and some clever use of PVC piping. Plus, it does it all without the glaring harshness you would get if you just turned the flashlight on and shone it on your subject.

This tip comes to us from Simon Ellingworth, award winning photographer and author of the photography education blog Lightism (and who's helped us with other photo tips in the past). He used a simple LED flashlight (available at any department store, but he specifically bought this Ultrafire model from Amazon, $12 USD), a 32" length of 1.5" PVC pipe, a PVC end-cap for the pipe, and some zip ties to keep the flashlight in place. From there, he cut out enough of the pipe for the flashlight to rest inside, assembled the whole thing, and turned it on. All of the parts only cost him about ?20 including the cost of the flashlight (about $30 USD), but since the flashlight is a bit cheaper for us, you'll probably come in lower if you make this yourself.

If this looks familiar to his previously mentioned glowstick light, it's because he used the same parts?the LED flashlight provides a brighter, more even light, but he notes you still have to play with the angles to get it looking just right. Hit the link below to see how he made it, and some sample photos he took with the light wand?you'll agree, they look great.

LED Flashlight photography: How to Make an Ice Light | Lightism via Lightism on Facebook

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/sD2LELSLKMg/transform-an-led-flashlight-into-an-affordable-ice-light-for-beautiful-evenly-lit-photos

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